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Table 3 Levels of RvD1 and cytokine in adolescent patients with MDD after treatment

From: The relationship between serum resolvin D1, NLRP3, cytokine levels, and adolescents with first-episode medication-naïve major depressive disorder

 

Pre-MDD (n = 48)

 

Post-MDD (n = 48)

t/Z

P-value

HDRS

25.58 ± 5.90

 

14.48 ± 6.14

9.217

<0.001*

RvD1 (pg/ml)

400.83 ± 91.83

 

340.89 ± 82.00

5.768

<0.001*

NLRP3 (pg/ml)

915.65 ± 148.13

 

766.08 ± 184.60

4.657

<0.001*

IL-1β (pg/ml)

57.08 ± 11.96

 

46.21 ± 9.87

3.627

0.001*

IL-18 (pg/ml)

261.79 ± 254.59

 

254.59 ± 41.77

0.661

0.512

IL-4 (pg/ml)

31.98 ± 4.87

 

38.52 ± 6.87

-5.289

<0.001*

  1. For continuous variables, data were presented as M ± SD. P-value was calculated using the paired t-test for normally distributed or the Mann-Whitney paired nonparametric test for nonnormally distributed
  2. *Statistically significant: P < 0.05
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BMC Psychiatry

ISSN: 1471-244X

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