The relationship between serum resolvin D1, NLRP3, cytokine levels, and adolescents with first-episode medication-naïve major depressive disorder

Table 2 Serum RvD1, NLRP3, and cytokines comparisons between adolescent MDD and the HCs

	Depressive adolescents (n = 48)	Healthy control (n = 30)	t/Z	P-value
RvD1(pg/ml)	400.83 ± 91.83	290.91 ± 76.21	5.479	<0.001*
NLRP3(pg/ml)	915.65 ± 148.13	887.96 ± 156.44	0.786	0.434
IL-1β(pg/ml)	57.08 ± 11.96	57.70 ± 11.68	-0.216	0.829
IL-18(pg/ml)	261.79 ± 54.59	265.78 ± 40.90	-0.369	0.713
IL-4(pg/ml)	31.98 ± 4.87	29.00 ± 5.60	2.407	0.019*

For continuous variables, data were presented as M ± SD. P-value was calculated using an independent sample T-test for normally distributed or the Mann-Whitney nonparametric test for nonnormally distributed
*Statistically significant: P < 0.05

ISSN: 1471-244X